SmartCell Clinic

The development of modern medicine is directed towards regenerative technologies. It is those that allow us to be closer to the natural mechanisms of treating diseases and stimulating protective mechanisms. Regenerative technologies enable using your own tissues to repair damage that has occurred as a result of illness or injury.
Today, modern traumatology, surgery, neurology, and other fields of medicine cannot be imagined without regenerative technologies. They are used for treating joints, various kinds of injuries, burns, wounds, post-stroke and post-infarction states, and other pathologies.
Moreover, regenerative technologies are used in aesthetic medicine for aging prevention and correction.

The term regenerative medicine encompasses all medical, technical, and biological aspects of scientific and practical directions for restoring the structure and function of damaged tissues and organs including cell technologies and application of cell technology products such as cell therapy, tissue engineering, creation and transplantation of artificial technical constructions.
Modern biological technologies require a well-established material, scientific and technical base and human resources.
In November 2012, in order to develop biotechnologies in medicine and cosmetology, the biotechnology company SmartCell was established in Odessa. The premises and equipment of the laboratory meet European and International GMP standards.

BENEFITS&ACHIEVEMENTS

  • Fully licensed laboratory: we are among 12 Ukrainian enterprises that have received licenses for their business.
  • Premises and the latest laboratory equipment (Japan) that meet European and International GMP standards.
  • Highly-qualified staff with long and successful experience.
  • The work is carried out in strict accordance with the global standards of cell cultivation.
  • A high speed of performing biotechnology operations.
  • Adherence to strict standards of quality and safety of biotechnology at all stages of biomaterial producing ensures its complete safety and the highest quality.
  • 9 patents for our unique inventions which are in high demand and successfully applied in different fields of medicine.
  • Our specialists made presentations at more than 30 international and local conferences and congresses.
  • We have trained more than 450 specialists.
  • Our cultures have been sent to the best Ukrainian clinics and to 12 countries abroad.
  • Thanks to SmartCell successful results, more than 2600 patients have been successfully treated by our general partner, the Ukrainian Institute of Plastic Surgery VIRTUS.

Stem cell therapy is a promising direction in medicine based on the application of the regenerative potential of the stem cells of the body in order to treat a wide range of severe diseases and restore from injuries as well as combat premature aging.

In Ukraine, treatment with stem cells was introduced into practice ten years ago. Since then, the numerous studies have been conducted and data on the beneficial effects of that approach to the treatment of more than a hundred serious diseases have been obtained. In some cases, it is virtually the only method of treatment.

Mesenchymal stem cells

Multipotent mesenchymal stem cells (MSCs), an important (and relatively rare) population of SC of the adult body, have a wide range of potential applications in regenerative medicine. MSCs can be isolated from the bone marrow and adipose (fat) tissue. Unlike the bone marrow, adipose tissue is more accessible for the cell extraction.

MSCs are capable of differentiation into adipocytes, chondrocytes, cardiomyocytes, osteocytes, neurogenic cells. Moreover, therapy with stem cells of this type contributes to the effective body recovery.

Due to the application of autologous (own patient’s cells) MSCs, there is no need for searching and obtaining donor biomaterials for treatment as well as the need for immunosuppressive therapy – MSCs have the immunosuppressive effect on immune cells.

Below we have described several basic treatment programs.

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Neurodegenerative disease is an umbrella term for a range of human NS conditions which arise from the death of neurons. Infections, intoxications, physical trauma, metabolic disorders, hereditary predisposition can be the factors.

Today, it is possible to diagnose neurodegenerative diseases in the early stages, but there is no complete cure for many of them. Supportive and behavioral therapy, constant medication, significant limitations seem to be all available offers of conventional medicine.

Autologous cell therapy has become a real breakthrough in the treatment of severe neurological diseases. To stop the development of degenerative changes in the brain tissues has proved to be possible in practice giving a second chance to the patients and hope to their families.

Effects of Cell Technologies for Neurodegenerative Diseases

  • Spinal cord and brain injuries: restoring functions of pelvic organs, reducing movement disorders, the possible appearance of the sensitivity of a mosaic type.
  • Alzheimer’s disease: restoring cognitive functions, ability to live independent meaningful life, the return of patient’s capacity.
  • Parkinson’s disease: stopping degenerative brain processes.
  • Multiple sclerosis:restoring myelin; normal transmission rate of nerve impulses; regeneration of brain and spinal cord cells on the sites of nerve tissue replaced by connective scar tissue; normalizing the immune system with the cessation of autoimmune “attacks” on the nervous system; restoring motor functions, ability to move independently and care of oneself.
  • Amyotrophic lateral sclerosis: stabilizing the patient’s condition; improving neurological functions; reduction in a loss of muscle mass.
  • Myopathy: improving metabolic processes in muscle tissue; preventing the disintegration of muscle fibers and their replacement by connective tissue; improving muscle trophism; an increase in the mass of active elements; a significant decrease in muscle weakness; normalizing CK value.
  • Treatment of stroke: formation of new vessels; contributing to the survival of damaged neurons in the brain; a burst of energy; improving motility; speech restoration.
  • Post-stroke states: improvement of functions of weak/paralyzed limbs; the return of the ability to walk and speak; improving blood supply to the brain; reducing the formation of glial scars and cysts; prevention of significant impairment of the central nervous system; promoting complete rehabilitation.
  • Ischemic diseases: possibility to preserve limbs; providing critical care (pre-gangrene); capillary neovascularization and collateral growth.

Orthopedics is concerned with the correction or prevention of deformities and impaired functions of the muscular-skeletal system. Pathological abnormalities can be congenital in nature or be the consequence of disease and/or trauma.

Traumatology and orthopedics are interconnected: mechanical, physical, and chemical damage causes local and general changes in the body.

Orthopedic diseases are classified by their nature/localization into:

  • degenerative diseases: arthrosis, muscle atrophy, osteoporosis, degenerative disc disease, osteochondrosis;
  • congenital and acquired orthopedic abnormalities: changes in posture, scoliosis, flat foot, transverse flatfoot, etc;
  • inflammatory rheumatic diseases: spondylitis and rheumatoid arthritis, osteomyelitis, diabetic neuropathy with foot deformities, hallux valgus deformity;
  • oncological diseases: vertebral and joint tumors;
  • injuries: fractures, ligament ruptures and injuries

Until now, orthopedic treatment has involved non-operative (conservative) therapy and surgery.

Regenerative medicine is a fundamentally new form of therapy for the treatment of degenerative joints, muscles, and ligaments based on autologous mesenchymal stem cell (MSC) therapy.

The course of therapy provides a symptomatic improvement within a few weeks and months. This innovative technology offers the opportunity to preserve joints, postpone their prosthetics, and improve quality of life.

Benefits

  • High efficacy; often, it is the only method of treatment.
  • A low invasive procedure.
  • Outpatient therapy.
  • A real opportunity to significantly delay/avoid surgery and disability.
  • An excellent alternative in case of drug intolerance (e.g., antirheumatic drugs, cortisone).
  • Acceleration of self-healing processes in the body (e.g., after fractures, osteonecrosis, soft tissue rupture).
  • Universality: MSCs can be used as monotherapy/combined with plastic surgery/combined with laser technologies.
  • A simple procedure.
  • Clinically proven safety: no side-effects.

Diabetes mellitus is a chronic disease that develops due to absolute or relative insulin deficiency. Lack or of insulin, or inability of the body tissues to properly use insulin causes the rise in blood glucose levels – hyperglycemia, which is dangerous for almost all body systems.

There two types of diabetes:

Type 1 diabetes results from the pancreatic cells failed to produce the sufficient amount of insulin.

Type 2 diabetes results from the body’s resistance to insulin produced.

Stem cell therapy for diabetes: choose life without limits.

Stem cells have a unique property – the capacity of transforming into any cell type including endodermal cells:

  • Stem cell therapy is very effective for type 1 diabetes: SCs transform into pancreatic cells responsible for insulin production, thus, damaged tissues restore. The patient has a real chance to overcome insulin dependence or at least reduce the insulin daily dose by half.
  • For type 2 diabetes, pancreatic cells responsible for insulin production are cultivated in vitro from autologous MSCs; then cells are implanted into the pancreas. After a single administration of autologous MSCs, patients with first-stage diabetes have normal levels of glycosylated hemoglobin and blood glucose, i.e. these patients no longer need insulin injections and immunosuppressive therapy.

The therapeutic effect: normalizing the pancreatic function, improving the patient’s condition. Stem cell therapy strengthens the immune system and restores the cardiovascular system: it is especially important for diabetic patients because the disease is often complicated by a serious impairment of blood circulation, particularly in small vessels of the extremities.

The processes of aging in the body begin at 30. Today, those, who strive to meet the requirements of the modern world and want to get the optimal rejuvenating result as naturally as possible, have a unique opportunity: rejuvenation by autologous (their own) stem cells (hereinafter – SC).

Aging of the body is associated with following symptoms:

  • male and female hormonal disorders;
  • chronic septic processes;
  • immunodeficiency conditions;
  • metabolic disorders;
  • general weakness;
  • fast fatigability;
  • a decrease in work capacity;
  • violations of attention and memory;
  • drowsiness;
  • early wrinkles;
  • weakened potency;
  • dizziness and tinnitus;
  • violations of appetite;
  • in menopausal women: hot flashes, sleep disorders, irritability, headaches, palpitation, weakness, anxiety.

The main cause of aging is a decrease in the pools of SCs and a decrease in their potential. It is SCs that are able to acquire the properties and abilities of cells performing a particular role in the body. Therefore, they are called the “gold reserve” of the body!

The rate of natural renewal of the body starts decreasing from a certain age. In order to trigger SCs with a “necessary signal”, the therapy implying the administration of sufficient quantity of autologous mesenchymal stem cells (AMC) is required.

Despite the fact that in elderly patients the recovery process is even more obvious, it is necessary to start therapy as early as possible – in this case only, the therapy will have a powerful PREVENTIVE effect!

Take the advantage of the achievements of modern regenerative medicine: the best result is a natural result!

SmartCell CLINIQUE — NEW QUALITY OF YOUR LIFE

Medical services:

Neurodegenerative diseases

Traumatology

Diabetes Mellitus

Stem Cell Rejuvenation

The clinic is equipped with an internal reception and a separate entrance to ensure the anonymity of patients. It is guarded around the clock.

The coordinating doctor stays in touch with the patient 24/7 by phone and instant messengers. An interpreter accompanies the patient during their stay in the clinic. We keep in touch even after the patient returns home to receive feedback and continue treatment remotely.

Hospital wards are spacious and comfortable, they resemble rooms in a prestigious hotel. The clinic has a restaurant with a special diet menu. For the period of stay in the country, the patient and accompanying person are provided with a room in the central metropolitan hotel. All transfers to the clinic, to the hotel and to the airport are organized by the clinic at its own expense.

You do not need to search for information, compare prices, book tickets and accommodation, coordinate travel dates with a doctor, hire an interpreter … We take care of all the arrangements for your trip.