Ensure the healthy future
Metabolism is stabilized. Man lose weight.
It is possible to avoid the development of cardiovascular disease and type 2 diabetes. With metabolic syndrome, there are risks of such diseases.
A person can lead a more active lifestyle.
Fatigue and apathy disappear.
No shortness of breath, headache, night sweats and drowsiness after meat-eating.
Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications
… Mesenchymal stem cells are multipotent cells with the potential to differentiate into a variety of cell lineages including fat, bone, cartilage, muscle, and marrow stroma . Although adipogenesis is a multistep process involving many cellular intermediates, for practical purposes it is currently characterized in two major phases: the determination phase and the terminal differentiation phase [16–18]. The determination phase involves commitment of a pluripotent stem cell into the adipocyte lineage [16–18]. In the terminal differentiation phase, the fibroblastic preadipocyte takes on characteristics of the spherical mature adipocyte, in that it can synthesize and transport lipids and secrete adipocyte-specific proteins, and it contains the machinery necessary for insulin sensitivity [16–18].
Stem cell therapy for obesity-induced metabolic disorders
Stem cells have the potential to grow into other tissue types such as bone, cartilage and muscle, making them suitable for treating metabolic disorders such as diabetes, insulin resistance and high levels of blood lipids.
A combination of high food intake and lack of physical activity increases fat storage in the body that puts stress on the metabolic pathways, eventually leading to metabolic dysfunction and disorders. Long-term use of drugs such as metformin, used to manage diabetes, cause adverse effects.
In search of a safer alternative, scientists from the Manipal Academy of Higher Education and Jain University in Bangalore, India, prepared three different stem-cell-based formulations. They then injected separate groups of obese mice with the different formulations and compared their efficacy with that of metformin.
All the formulations significantly lowered glucose and serum triglyceride levels in the mice. Besides, the formulations significantly reduced serum insulin levels. Of all the formulations, stem cell suspension remarkably reduced inflammation and triglycerides in the liver….