The Neurocognitive disorders a broad range of diseases of central and peripheral nervous system. It’s only in less than 5% of the cases a clear genetic link has been established, however, majority is sporadic and driven by a combination of genetic and environmental factors. Alzheimer’s and Parkinson’s are the most common and renowned disorders that largely affect the elderly population. However, neural degeneration and associated loss of memory in these diseases is not a normal part of ageing as it occurs only in few, not all elderly people. It is considered that neurodegeneration is a generalized systemic disorder that also inflicts other organs, although it is most pervasive in neurons. Interestingly, it is not cell-autonomous, that means multiple cell types such as astrocytes, oligodendroglia, Schwann cells etc. are also involved. Therefore, therapeutic interventions for neurodegenerative diseases remain the most daunting task today. The emerging new technology like stem cells based therapeutics can offer some respite and is becoming an active area of research.

Stem cells are actively and successfully used to treat neurocognitive disorders.

Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs memory formation and disrupts neurocognitive function. This neuropathy is characterized by neural loss, neurodegeneration, and formation of amyloid plaques and neurofibrillary tangles. Approved medications provide only symptomatic relief without affecting AD progression….

Autism

Autism or autism spectrum disorder (ASD) is a term, unifying a wide range of conditions characterized by repetitive behavior, difficulties with social interaction and speech. ASD is a general name for a variety of subtypes of the disorder, every case of autism is unique in its manifestations…

Cerebral Palsy

Cerebral palsy is a term that unites a group of chronic diseases characterized by movement disorders. The main cause is abnormal development or damage of those parts of the brain that control movement, balance, and coordination. Often the problems develop during pregnancy, but they can also appear shortly after the birth or during childbirth…

Developmental Delay

Children do not grow and develop according to a timetable but there are conditions that shouldn’t be neglected. Developmental delay is more than just being a little behind children of the same age. Minor differences, like not rolling over by 4 months, shouldn’t cause concern…

Parkinson’s disease (PD)

Parkinson’s disease is one of the most severe and mysterious illnesses of modern times. It is a progressive chronic disease that usually affects older people. PD is a degenerative disorder of the central nervous system that results in tremor, loss of automatic movements, rigid muscles, problems with speech and writing, slowed movements and other symptoms…

Rehabilitation after stroke and neurological diseases

Rehabilitation helps someone who has had a stroke relearn skills that are suddenly lost when part of the brain is damaged. Equally important in rehabilitation is to protect the individual from developing new medical problems, including pneumonia, urinary tract infections, injury due to fall, or a clot formation in large veins…